You want to know if AutoCAD® Civil 3D® runs on the Windows Vista™ operating system.
Autodesk Civil 3D® 2007 – is not supported on Windows Vista™.
AutoCAD Civil 3D® 2008 – is supported only on Windows Vista 32-bit.
AutoCAD Civil 3D® 2009 – is supported on Windows Vista 32-bit and 64-bit (on 64-bit, it runs in 32-bit compatibility mode).
For more information on this issue, including potential causes, workarounds, and resolutions, see: AutoDesk KB Article TS1067086.