HomeSite compatibility on Windows Vista
HomeSite 5.5 was released more than three years before Windows Vista became publicly available and does not officially support this new operating system. However, we are not currently aware of any major issues that would adversely affect customer use of HomeSite on Windows Vista. For more information on Adobe product support in general for Vista, see How Adobe Products Support Windows Vista.
While HomeSite 5.5 should work well for most users using the default Vista settings, some users have reported that they need to run HomeSite in Windows XP Compatibility mode and as an administrator.