iSCSI Favorite Targets may need to be re-created if there is a network configuration change on the initiator system
Consider the following scenario. You have set up a Favorite Target connection to an iSCSI Target using the Microsoft iSCSI Initiator. You make a network configuration change on the initiator system, and restart the system. Once the system has started, you may notice that the LUNs presented by the iSCSI Target are inaccessible. Also, under the Targets tab in the iSCSI Initiator User Interface, you may notice that the Favorite Target is stuck in a “Reconnecting…” state.
For more information on this issue, including potential causes, workarounds, and resolutions, see: Microsoft KB Article KB967476.